Opportunity Information: Apply for PA 18 314
The Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research (Administrative Supplement), funding opportunity number PA 18-314, is a discretionary NIH grant opportunity designed to strengthen the national innovation pipeline that grows out of biomedical and public health research. The core idea is to help turn early scientific and technical advances into real-world technologies, products, and services that deliver tangible benefits to society. Rather than funding brand-new standalone research projects, this announcement focuses on building commercialization and translation skills around work that is already underway, reinforcing the broader NIH goal of moving promising discoveries beyond the lab and closer to patients, providers, and communities.
A central feature of the program is education and training in translation and commercialization. The I-Corps at NIH model emphasizes practical learning for researchers and technologists who may have strong scientific expertise but limited exposure to market needs, customer discovery, regulatory and reimbursement realities, and business-model design. In practice, the program is meant to teach teams how to evaluate whether a technology solves an important problem, who the end users and decision-makers are, what evidence is needed for adoption, and what steps are required to responsibly and competitively enter the marketplace. This training orientation places the opportunity in an “Education, Environment, Food and Nutrition, Health, Income Security and Social Services” activity category, reflecting its workforce and ecosystem-building intent in addition to its technology-translation purpose.
Eligibility is tightly tied to the federal small business innovation programs. The eligible applicants are small businesses, and the supplements are specifically aimed at entities that already hold active NIH- or CDC-related SBIR or STTR Phase I awards. Under this FOA, participating NIH and CDC Institutes and Centers continue to provide administrative supplement awards to currently funded Phase I SBIR/STTR grantees, meaning the funding is structured as an add-on to an existing award rather than a separate, independent grant. This structure signals that the supplement is intended to accelerate the path from Phase I feasibility work to a clearer commercialization strategy, using the I-Corps curriculum and customer discovery process to reduce uncertainty and improve downstream translational decisions.
The announcement also makes clear that it is limited to U.S.-based participation. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components as defined in the NIH Grants Policy Statement are not allowed. In other words, applicants must be domestic small businesses with qualifying existing SBIR/STTR Phase I funding, and the supported work under the supplement must not involve foreign components as part of the project’s execution.
From an administrative and timing perspective, the opportunity is issued by the National Institutes of Health, with a creation date of October 12, 2017, and an original closing date listed as December 18, 2017. The opportunity is categorized as a grant mechanism, and it is cross-referenced to multiple CFDA numbers (now often referred to under Assistance Listing numbers) spanning many NIH institute portfolios, indicating that multiple NIH and CDC components may participate depending on institute-specific priorities and the underlying SBIR/STTR award. Details such as the award ceiling and expected number of awards are not specified in the provided source text, which is consistent with some supplement announcements where amounts and counts can vary by institute, availability of funds, and the pool of eligible active Phase I awards.
Overall, PA 18-314 is best understood as an NIH and CDC translational support pathway that uses the I-Corps training framework to help SBIR/STTR Phase I small businesses validate real market needs, sharpen commercialization plans, and improve the likelihood that federally funded biomedical innovations successfully transition into products and services with public benefit.Apply for PA 18 314
- The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research (Admin Supp)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084, 93.113, 93.121, 93.172, 93.173, 93.242, 93.262, 93.273, 93.279, 93.350, 93.394, 93.395, 93.847, 93.853, 93.855, 93.865, 93.866.
- This funding opportunity was created on 2017-10-12.
- Applicants must submit their applications by 2017-12-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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FAQs: I-Corps at NIH Program for NIH and CDC Translational Research (Administrative Supplement) - PA 18-314
What is the PA 18-314 opportunity?
PA 18-314 is the Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research offered as an administrative supplement. It is a discretionary NIH grant opportunity focused on strengthening the innovation pipeline that grows out of biomedical and public health research by helping teams translate early advances into real-world technologies, products, and services.
What is the main purpose of this program?
The core purpose is to help move promising scientific and technical advances beyond the lab and closer to patients, providers, and communities. The opportunity is designed to build commercialization and translation capability around work that is already underway, rather than supporting a brand-new standalone research project.
Is this funding intended for brand-new research projects?
No. Based on the description provided, this announcement focuses on building commercialization and translation skills around existing funded work. It is structured as an add-on (administrative supplement) to an active award, not a separate independent grant for a new project.
What kinds of activities does I-Corps at NIH emphasize?
The program emphasizes education and training in translation and commercialization. It is designed for researchers and technologists who may have strong scientific expertise but limited exposure to market needs, customer discovery, regulatory and reimbursement realities, and business-model design.
What is meant by "customer discovery" in this context?
Within the I-Corps model described, customer discovery refers to the practical process of evaluating whether a technology solves an important problem, identifying end users and decision-makers, and understanding what evidence is needed for real-world adoption.
What kinds of questions does the training help teams answer?
The training is intended to help teams clarify: whether the technology addresses an important need, who the users and decision-makers are, what adoption evidence will be required, and what steps are needed to enter the marketplace responsibly and competitively (including regulatory and reimbursement considerations).
How is this opportunity categorized?
The opportunity is placed in an "Education, Environment, Food and Nutrition, Health, Income Security and Social Services" activity category. This reflects its workforce development and ecosystem-building intent in addition to its technology translation focus.
Who is eligible to apply?
Eligibility is limited to small businesses. More specifically, the supplements are aimed at small businesses that already hold active NIH- or CDC-related SBIR or STTR Phase I awards.
Do applicants need to have an existing SBIR/STTR award?
Yes. The supplement is specifically intended for currently funded Phase I SBIR/STTR grantees with active NIH- or CDC-related Phase I awards.
What does it mean that this is an administrative supplement?
An administrative supplement means the funding is structured as an add-on to an existing award rather than a separate, standalone award. As described, participating NIH and CDC Institutes and Centers provide supplement awards to currently funded Phase I SBIR/STTR grantees.
What stage of SBIR/STTR does this support target?
Based on the provided information, the target population is Phase I SBIR/STTR awardees (active Phase I awards). The supplement is positioned to accelerate the path from Phase I feasibility work to a clearer commercialization strategy through I-Corps training and customer discovery.
Are non-U.S. entities eligible to apply?
No. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply under this opportunity.
Can a U.S. organization include non-domestic components?
No. Non-domestic components of U.S. organizations are not eligible, and foreign components (as defined in the NIH Grants Policy Statement) are not allowed as part of the project’s execution.
Who issues this funding opportunity?
The opportunity is issued by the National Institutes of Health (NIH), and it is described as covering NIH and CDC translational research through participating Institutes and Centers.
What is the funding opportunity number?
The funding opportunity number is PA 18-314.
What type of funding mechanism is this?
It is categorized as a grant mechanism and is provided in the form of an administrative supplement to an existing eligible SBIR/STTR Phase I award.
When was this opportunity created and when did it close?
The creation date listed is October 12, 2017, and the original closing date listed is December 18, 2017.
Are the award ceiling and expected number of awards provided?
No. The provided description states that details such as the award ceiling and expected number of awards are not specified in the source text, which can be typical for supplement announcements where amounts and counts may vary by institute, available funds, and the pool of eligible awards.
Does the opportunity involve NIH only, or NIH and CDC?
It is described as the I-Corps at NIH Program for NIH and CDC Translational Research. Participating NIH and CDC Institutes and Centers may provide administrative supplement awards to eligible Phase I SBIR/STTR grantees.
Why are multiple CFDA (Assistance Listing) numbers mentioned?
The opportunity is cross-referenced to multiple CFDA numbers spanning many NIH institute portfolios. This indicates that multiple NIH and CDC components may participate depending on institute-specific priorities and the underlying SBIR/STTR award.
What is the overall benefit of this program for eligible small businesses?
The program aims to help SBIR/STTR Phase I small businesses validate real market needs, sharpen commercialization plans, and reduce uncertainty in downstream translational decisions, improving the chances that federally funded innovations transition into products and services with public benefit.
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Applicants who have applied for this opportunity (PA 18 314) also looked into and applied for these:
| Funding Opportunity |
|---|
| Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) Apply for PA 18 403 Funding Number: PA 18 403 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 - No Independent Clinical Trials) Apply for PA 18 373 Funding Number: PA 18 373 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 - Independent Clinical Trials Not Allowed) Apply for PA 18 375 Funding Number: PA 18 375 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Quantitative Research Development Award (Parent K25 - No Independent Clinical Trials) Apply for PA 18 396 Funding Number: PA 18 396 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Pathway to Independence Award (Parent K99/R00 - Independent Clinical Trial Not Allowed) Apply for PA 18 398 Funding Number: PA 18 398 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) Apply for PA 18 484 Funding Number: PA 18 484 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Academic Research Enhancement Award (Parent R15 Clinical Trial Not Allowed) Apply for PA 18 504 Funding Number: PA 18 504 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $300,000 |
| Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research (Admin Supp - Clinical Trial Not Allowed) Apply for PA 18 517 Funding Number: PA 18 517 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) Apply for PA 18 574 Funding Number: PA 18 574 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) Apply for PA 18 575 Funding Number: PA 18 575 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) Apply for PA 18 586 Funding Number: PA 18 586 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp - Clinical Trial Optional) Apply for PA 18 591 Funding Number: PA 18 591 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Successor-in-Interest (Type 6 Parent Clinical Trial Optional) Apply for PA 18 589 Funding Number: PA 18 589 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Change of Grantee Organization (Type 7 Parent Clinical Trial Optional) Apply for PA 18 590 Funding Number: PA 18 590 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp - Clinical Trial Not Allowed ) Apply for PA 18 592 Funding Number: PA 18 592 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) Apply for PA 18 648 Funding Number: PA 18 648 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplement for Research on Sex/Gender Influences (Admin Supp - Clinical Trial Optional) Apply for PA 18 658 Funding Number: PA 18 658 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31) Apply for PA 18 666 Funding Number: PA 18 666 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 18 668 Funding Number: PA 18 668 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) Apply for PA 18 671 Funding Number: PA 18 671 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
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