Opportunity Information: Apply for RFA AG 27 007
This funding opportunity, RFA-AG-27-007, is a National Institutes of Health (NIH) Notice of Funding Opportunity to renew and support the next five-year award period for the Clinician-Scientist Transdisciplinary Aging Research Coordinating Center (Clin-STAR CC). The program is run under a cooperative agreement mechanism (U24), which typically means the awardee will work in close partnership with NIH program staff rather than operating entirely independently. The notice also specifies "Clinical Trial Not Allowed," so the coordinating center is not being funded to run clinical trials; instead, it is meant to operate as a national coordination, mentoring, and networking resource that strengthens the aging research workforce and accelerates interdisciplinary, patient-centered aging science.
The core mission of the Clin-STAR Coordinating Center is to function as a national resource for clinician-investigators from many clinical specialties and disciplinary backgrounds who want to build careers focused on aging research. The National Institute on Aging (NIA) is essentially looking to build on its prior investments by sustaining and expanding a platform that helps clinicians become productive aging researchers, regardless of whether they come from internal medicine, surgery, emergency medicine, psychiatry, neurology, rehabilitation, nursing, dentistry, and other fields where older adults are a major part of clinical care but aging research training may be unevenly available.
The NOFO lays out several connected goals. One major focus is dissemination of scientific and research knowledge in aging, meaning the coordinating center is expected to help clinicians gain access to the concepts, methods, and evidence base needed to do strong aging research (for example, geriatrics-focused research design considerations, measurement approaches relevant to older adults, and frameworks for studying multimorbidity, functional outcomes, cognition, disability, and patient priorities). A second major focus is building networking and collaboration between established clinician-scientist leaders in aging research and the broader pool of clinician-investigators across specialties who want to pivot into aging-focused work. In practical terms, this implies convening communities of practice, creating structured opportunities for collaboration, and lowering the friction that often prevents cross-specialty teams from forming.
A third pillar is mentoring and career development support for emerging clinician-scientists who are committed to pursuing aging research within their home specialty or discipline. Rather than training people to leave their specialty, the program is geared toward helping them embed aging research where they already practice and teach, which is important because improving care for older adults depends on better aging science inside every clinical field, not only geriatrics. Finally, the coordinating center is expected to help advance interdisciplinary research projects in aging. Because this is a coordinating center rather than a traditional research project grant, that advancement is likely to come through matchmaking, pilot project facilitation, consultative support, shared resources, and structured project development activities that help teams refine questions and become competitive for other NIH research funding.
The intended long-term outcome is a multi-faceted national research platform that contributes to improved, patient-centered care for older adults across specialties and disciplines. In other words, the coordinating center is a workforce and infrastructure investment: it is meant to help create and support clinician-scientists who can generate the evidence that changes everyday care for older adults in a wide range of settings, from hospitals and clinics to community and long-term care environments.
From a funding and competition standpoint, the opportunity is relatively focused: NIH expects to make one award. The maximum award amount listed is $1,500,000 (award ceiling), and the application closing date is September 29, 2026. The opportunity is categorized as discretionary and falls under the health activity category, with CFDA numbers 93.310 and 93.866.
Eligibility is broad within the United States and includes many common applicant types, such as public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and non-501(c)(3) nonprofits), for-profit organizations (other than small businesses) and small businesses, as well as various government entities (state, county, city/township, special district), independent school districts, public housing authorities/Indian housing authorities, and eligible Native American tribal governments and tribal organizations. However, the NOFO is explicit that non-U.S. entities cannot apply: non-domestic (non-U.S.) organizations are not eligible, and non-domestic components of U.S. organizations are also not eligible. At the same time, "foreign components" are allowed as defined by the NIH Grants Policy Statement, meaning a U.S. applicant may be able to include certain internationally based elements or collaborations if they meet NIH policy requirements and are justified, even though the primary applicant organization and its components must be domestic.
Overall, this NOFO is best understood as a renewal competition to operate a national coordinating center that grows the pipeline of clinician-scientists in aging, connects trainees and early-career investigators with experienced mentors and collaborators, and stimulates cross-disciplinary aging research that ultimately improves outcomes and care experiences for older adults. For the most precise expectations about required components, milestones, governance, deliverables, and allowable activities, applicants are directed to the detailed eligibility and program requirements in Section III and other sections of the full NOFO.Apply for RFA AG 27 007
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Renewal of the Clinician-Scientists Transdisciplinary Aging Research (Clin-STAR) Coordinating Center (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310, 93.866.
- This funding opportunity was created on 2026-06-26.
- Applicants must submit their applications by 2026-09-29. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs): RFA-AG-27-007 (Clin-STAR Coordinating Center)
1) What is RFA-AG-27-007 funding?
RFA-AG-27-007 is a National Institutes of Health (NIH) Notice of Funding Opportunity (NOFO) to renew and support the next five-year award period for the Clinician-Scientist Transdisciplinary Aging Research Coordinating Center (Clin-STAR CC). The focus is on operating a national coordinating center that strengthens the clinician-scientist workforce in aging research through coordination, mentoring, networking, and research-enabling activities.
2) Which NIH Institute is associated with this opportunity?
This opportunity is associated with the National Institute on Aging (NIA), which is building on prior investments to sustain and expand a national platform for clinician-investigators pursuing aging research.
3) What mechanism will be used for the award?
The award uses a cooperative agreement mechanism (U24). In general, a U24 cooperative agreement indicates the awardee will work in close partnership with NIH program staff, rather than operating entirely independently.
4) Is this a clinical trial opportunity?
No. The NOFO specifies "Clinical Trial Not Allowed." The coordinating center is not being funded to run clinical trials. Instead, it is funded to serve as a national resource that coordinates, mentors, and connects clinician-investigators and helps accelerate interdisciplinary, patient-centered aging science.
5) What is the overall purpose of the Clin-STAR Coordinating Center?
The core mission is to function as a national resource for clinician-investigators across many clinical specialties and disciplinary backgrounds who want to build careers focused on aging research. The center is intended to help clinicians become productive aging researchers and to strengthen aging research capacity across the clinical landscape.
6) Who is the coordinating center meant to serve?
The center is intended to serve clinician-investigators from a wide range of specialties and disciplines, including (as examples mentioned) internal medicine, surgery, emergency medicine, psychiatry, neurology, rehabilitation, nursing, and dentistry, as well as other fields where older adults are a major part of clinical care.
7) What are the main goals described in the NOFO?
The NOFO describes several connected goals, including: (1) dissemination of scientific and research knowledge in aging; (2) building networking and collaboration between established clinician-scientist leaders in aging research and clinician-investigators across specialties; (3) mentoring and career development support for emerging clinician-scientists committed to aging research within their home specialty; and (4) advancing interdisciplinary research projects in aging through coordinating-center functions.
8) What does "dissemination of scientific and research knowledge in aging" mean here?
Based on the description provided, dissemination includes helping clinicians access key concepts, methods, and evidence relevant to high-quality aging research. Examples mentioned include geriatrics-focused research design considerations, measurement approaches relevant to older adults, and frameworks for studying multimorbidity, functional outcomes, cognition, disability, and patient priorities.
9) How is networking and collaboration expected to be supported?
The coordinating center is expected to build networking and collaboration between established clinician-scientist leaders and clinicians across specialties who want to pivot into aging-focused work. In practical terms, this implies convening communities of practice, creating structured opportunities for collaboration, and lowering barriers that prevent cross-specialty teams from forming.
10) What kind of mentoring and career development support is emphasized?
The program emphasizes mentoring and career development support for emerging clinician-scientists who are committed to aging research while remaining grounded in their home specialty or discipline. The intent is not to train clinicians to leave their specialty, but to help embed aging research within each specialty where older adults receive care.
11) Does the coordinating center directly fund or conduct research projects?
This is described as a coordinating center rather than a traditional research project grant. The advancement of interdisciplinary aging research projects is expected to occur through activities such as matchmaking, pilot project facilitation, consultative support, shared resources, and structured project development support that helps teams refine questions and become competitive for other NIH research funding.
12) What is the long-term outcome NIH is aiming for?
The intended long-term outcome is a multi-faceted national research platform that contributes to improved, patient-centered care for older adults across specialties and disciplines. The coordinating center is positioned as a workforce and infrastructure investment to expand the pool of clinician-scientists who can generate evidence that improves care for older adults across many settings (including hospitals, clinics, community settings, and long-term care environments).
13) How many awards does NIH expect to make under this opportunity?
NIH expects to make one award.
14) What is the maximum award amount?
The maximum award amount listed (award ceiling) is $1,500,000.
15) What is the application due date?
The application closing date is September 29, 2026.
16) What is the award period described?
The opportunity is described as supporting the next five-year award period for the Clin-STAR Coordinating Center.
17) What type of funding category is this?
The opportunity is categorized as discretionary and falls under the health activity category.
18) What CFDA numbers are associated with this opportunity?
The CFDA numbers listed are 93.310 and 93.866.
19) What types of U.S. organizations are eligible to apply?
Eligibility is broad within the United States and includes public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and non-501(c)(3) nonprofits); for-profit organizations (other than small businesses) and small businesses; and various government entities (state, county, city/township, special district). Additional eligible entities listed include independent school districts, public housing authorities/Indian housing authorities, eligible Native American tribal governments, and tribal organizations.
20) Are non-U.S. (foreign) organizations eligible to apply?
No. The NOFO explicitly states that non-domestic (non-U.S.) organizations are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible.
21) Are any international elements allowed at all?
Yes, in a limited way. While the applicant organization and its components must be domestic, "foreign components" are allowed as defined by the NIH Grants Policy Statement. This suggests a U.S. applicant may be able to include certain internationally based elements or collaborations if they meet NIH policy requirements and are justified.
22) Is this opportunity best understood as a new center or a renewal competition?
Based on the description provided, it is best understood as a renewal competition to operate a national coordinating center and to sustain and expand a platform NIH has previously invested in.
23) What should applicants review for the most precise requirements and deliverables?
Applicants are directed to the full NOFO for precise expectations, including required components, milestones, governance, deliverables, allowable activities, and detailed eligibility requirements. The description specifically points to Section III and other sections of the full NOFO for these details.
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