Opportunity Information: Apply for RFA DA 24 068
This funding opportunity (RFA-DA-24-068) is a National Institutes of Health, National Institute on Drug Abuse (NIDA) cooperative agreement to support the HEAL Initiative through the Justice Community Overdose Innovation Network (JCOIN), Phase II. The basic premise is that the opioid crisis is heavily concentrated at the boundary between justice settings (jails, prisons, probation/parole, courts, reentry) and community health systems. Because people cycle between these systems, gaps in treatment, data sharing, continuity of care, and overdose prevention often show up most clearly during arrest, incarceration, release, and supervision. NIDA is using JCOIN to build a coordinated national research consortium that can test and scale approaches that improve how justice systems respond to opioid use disorder and overdose risk, while also strengthening links to community-based care.
JCOIN is intentionally structured as a tightly integrated network with three parts that are designed to work together rather than operate as separate projects. First are the Clinical Research Centers, each of which proposes a study that must be executed across at least five research performance sites, reflecting a strong emphasis on multi-site, real-world implementation. Second is a single Coordination and Translation Center, meant to harmonize operations across the network and help move findings into practice. Third, and the focus of this particular announcement, is a single Methodology and Advanced Analytics Resource Center. The applicant for this FOA is essentially competing to become the network-wide hub for study design support, analytic leadership, data methods, and advanced statistical and computational approaches that enable the whole JCOIN enterprise to produce reliable, comparable, and usable evidence.
The Methodology and Advanced Analytics Resource Center is expected to provide expertise and shared services that strengthen the scientific rigor and consistency of JCOIN’s work across justice and community contexts. In practical terms, this kind of center typically supports harmonized measures and common data elements, robust analytic plans for multi-site studies, methods for dealing with complex justice-health system data, and guidance on issues like missing data, clustering, site variation, implementation outcomes, mediation/moderation, and policy-relevant endpoints (including overdose events and treatment continuity). Because the work sits at the intersection of multiple systems, the center’s role usually includes helping studies navigate variation in local practices, heterogeneity in populations and settings, and the challenges of linking data across corrections, courts, treatment providers, and public health entities. The title also signals a focus on modern analytic capability (advanced analytics), which can include pragmatic trial analytics (even though this FOA is not itself for a clinical trial), causal inference approaches, predictive modeling for overdose risk, and methods that support translation of results into operational decision-making.
This award uses the cooperative agreement mechanism (UM1), which matters because it implies substantial NIH involvement during the life of the award. Unlike a traditional grant where the funded team operates more independently, a cooperative agreement generally means the awardee works in close partnership with NIDA and with the other JCOIN components, following network-wide governance, shared timelines, and coordinated deliverables. The “Clinical Trial Not Allowed” designation also clarifies that the applicant for this Resource Center should not propose to run an independent clinical trial under this award; the center is meant to provide methodological and analytic infrastructure and support to the network’s clinical research projects rather than serve as a trial-running entity itself.
Eligibility is broad and includes many domestic organization types: state, county, and city governments; special districts; independent school districts; public and state-controlled and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding higher education institutions in those categories); for-profit organizations other than small businesses; and small businesses. The announcement also explicitly notes additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, AANAPISI institutions, Hispanic-serving institutions, HBCUs, Tribally Controlled Colleges and Universities, faith-based or community-based organizations, and certain tribal governments that are not federally recognized. Foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible; however, foreign components as defined by the NIH Grants Policy Statement are allowed, meaning a U.S. applicant can include certain foreign elements if they meet NIH’s definition and justification requirements.
Administratively, the opportunity is listed under the NIH as the issuing agency, with a discretionary funding category and activity areas spanning education, health, and social services. The CFDA numbers associated with the announcement include 93.213, 93.279, and 93.865. The original closing date in the provided record is October 30, 2023, and the record does not specify an award ceiling or expected number of awards in the excerpt. Overall, the grant is aimed at selecting one central team to serve as the methodological backbone of JCOIN Phase II, enabling high-quality, comparable, and actionable research across multiple sites and jurisdictions, with the end goal of reducing overdose and improving evidence-based responses to opioid use disorder among justice-involved populations.Apply for RFA DA 24 068
- The National Institutes of Health in the education, health, income security and social services sector is offering a public funding opportunity titled "HEAL Initiative: Justice Community Overdose Innovation Network (JCOIN) - Phase II Methodology and Advanced Analytics Resource Center (UM1 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213, 93.279, 93.865.
- This funding opportunity was created on 2023-08-21.
- Applicants must submit their applications by 2023-10-30. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs) - RFA-DA-24-068 (JCOIN Phase II Methodology and Advanced Analytics Resource Center)
1) What is RFA-DA-24-068?
RFA-DA-24-068 is a National Institutes of Health (NIH), National Institute on Drug Abuse (NIDA) funding opportunity to support the HEAL Initiative through the Justice Community Overdose Innovation Network (JCOIN), Phase II. It is a cooperative agreement intended to strengthen how justice systems and community health systems respond to opioid use disorder (OUD) and overdose risk, especially where people move between incarceration/supervision and community care.
2) What is the main goal of this funding opportunity?
The main goal is to fund a single Methodology and Advanced Analytics Resource Center that serves as the network-wide hub for study design support, analytic leadership, and data/methods infrastructure across JCOIN Phase II. The center is intended to help JCOIN produce rigorous, consistent, comparable, and practice-relevant evidence across multiple justice and community settings.
3) How does this opportunity relate to the HEAL Initiative?
This award supports the HEAL Initiative by strengthening a coordinated research consortium (JCOIN) focused on reducing overdose and improving evidence-based responses to OUD among justice-involved populations.
4) What is JCOIN and why is it focused on justice and community settings?
JCOIN is a national research consortium built around the premise that the opioid crisis is heavily concentrated at the boundary between justice settings (such as jails, prisons, probation/parole, courts, and reentry) and community health systems. Because people often cycle between these systems, gaps in treatment access, continuity of care, data sharing, and overdose prevention can be most visible during arrest, incarceration, release, and supervision.
5) What are the major components of JCOIN Phase II?
JCOIN Phase II is structured as an integrated network with three components designed to work together:
- Clinical Research Centers that each propose a study implemented across at least five research performance sites.
- A single Coordination and Translation Center that harmonizes operations and supports translation of findings into practice.
- A single Methodology and Advanced Analytics Resource Center (the focus of this announcement) that provides network-wide methodological and analytic leadership.
6) What is being funded under this specific announcement?
This announcement funds one Methodology and Advanced Analytics Resource Center for JCOIN Phase II. The selected applicant becomes the network-wide hub for methodological support, analytics, and data methods that enable JCOIN studies to generate reliable and usable evidence.
7) Is this grant meant to fund multiple Resource Centers or a single one?
Based on the provided description, the intent is to fund a single Methodology and Advanced Analytics Resource Center to serve the entire network.
8) What kinds of support is the Methodology and Advanced Analytics Resource Center expected to provide?
The center is expected to provide expertise and shared services that strengthen scientific rigor and consistency across JCOIN studies. Examples described in the opportunity include:
- Support for harmonized measures and common data elements
- Robust analytic plans for multi-site studies
- Methods for working with complex justice-health system data
- Guidance on missing data, clustering, site variation, and heterogeneity
- Approaches for implementation outcomes, mediation/moderation, and policy-relevant endpoints
- Analytic approaches related to overdose events and treatment continuity
- Advanced analytics capabilities (for example, causal inference, predictive modeling for overdose risk, pragmatic trial analytics concepts) to support operational decision-making and translation
9) Does this opportunity allow the applicant to run a clinical trial?
No. The opportunity is marked "Clinical Trial Not Allowed." The Resource Center is intended to provide methodological and analytic infrastructure and support to the network's clinical research projects, not to run an independent clinical trial under this award.
10) What does it mean that the award mechanism is a cooperative agreement (UM1)?
A UM1 cooperative agreement indicates substantial NIH involvement during the life of the award. Rather than operating independently, the awardee is expected to work in close partnership with NIDA and with other JCOIN components, following network governance, coordinated timelines, and shared deliverables.
11) Who is the issuing agency?
The issuing agency is the National Institutes of Health (NIH), specifically the National Institute on Drug Abuse (NIDA).
12) What kinds of organizations are eligible to apply?
Eligibility is broad and includes a range of U.S.-based organizations, including:
- State, county, and city governments
- Special districts
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Federally recognized tribal governments
- Other tribal organizations
- Public housing authorities/Indian housing authorities
- Nonprofits with or without 501(c)(3) status (excluding higher education institutions in those nonprofit categories)
- For-profit organizations other than small businesses
- Small businesses
13) Are faith-based or community-based organizations eligible?
Yes. The opportunity explicitly notes faith-based or community-based organizations among additional eligible applicant categories.
14) Are minority-serving institutions specifically mentioned as eligible?
Yes. The announcement explicitly notes additional eligible applicant categories, including Alaska Native and Native Hawaiian Serving Institutions, AANAPISI institutions, Hispanic-serving institutions, HBCUs, and Tribally Controlled Colleges and Universities.
15) Can foreign institutions apply?
No. Foreign institutions are not eligible to apply.
16) Can a U.S. organization include non-U.S. components in the application?
Non-U.S. components of U.S. organizations are not eligible. However, foreign components (as defined by the NIH Grants Policy Statement) are allowed, meaning a U.S. applicant may include certain foreign elements if they meet NIH's definition and justification requirements.
17) What types of settings and systems is JCOIN focused on?
JCOIN focuses on the justice-community boundary, including jails, prisons, probation/parole, courts, and reentry, as well as community health systems and community-based treatment and public health entities. The aim is to address challenges that arise as people move across these settings.
18) Why is multi-site research emphasized in JCOIN?
The network is designed to test and scale approaches in real-world conditions across jurisdictions. The Clinical Research Centers are described as proposing studies that must be executed across at least five research performance sites, which creates a need for harmonized methods and comparable analytics across varied sites.
19) What kinds of data challenges is the Resource Center expected to address?
Based on the description, the Resource Center is expected to help studies handle complex justice-health data and cross-system variation, including challenges tied to:
- Differences in local practices across jurisdictions
- Heterogeneity in populations and settings
- Linking data across corrections, courts, treatment providers, and public health entities
- Missing data, clustering effects, and site-level variation
20) What outcomes or endpoints are highlighted as important?
The description points to policy-relevant endpoints, including overdose events and treatment continuity, along with broader implementation outcomes and evidence that is usable for operational decision-making in justice and community systems.
21) What activity areas does the opportunity fall under?
The opportunity is described as spanning activity areas in education, health, and social services.
22) What are the CFDA numbers associated with this funding opportunity?
The CFDA numbers listed for this announcement are 93.213, 93.279, and 93.865.
23) What is the closing date shown in the provided record?
The provided record lists an original closing date of October 30, 2023.
24) Does the excerpt specify the award ceiling or the expected number of awards?
No. The excerpt provided does not specify an award ceiling or the expected number of awards.
25) In simple terms, what does success look like for this Resource Center?
Success would look like providing the analytic and methodological backbone that helps JCOIN studies produce consistent, scientifically rigorous, and comparable evidence across multiple sites and jurisdictions, and helping ensure results are usable for improving OUD treatment continuity and overdose prevention for justice-involved populations.
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