Opportunity Information: Apply for RFA DE 27 001
The NIH is soliciting applications for a single Community Engagement Evaluation and Data Coordination (CEED) Hub under a cooperative agreement mechanism (U01) to support a broader Community-Based Participatory Research (CBPR) consortium called Advancing Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All. The CEED Hub is designed to function as the coordinating center for ADAPT, helping multiple, separately funded CBPR projects work in a consistent, collaborative, and data-driven way to improve oral health outcomes and reduce inequities. This funding opportunity is explicitly marked as Clinical Trial Not Allowed, meaning the CEED Hub itself is not intended to run clinical trials; instead, it provides coordination, evaluation, and analytic infrastructure that enables the consortium to operate effectively.
At a high level, ADAPT is structured so that individual CBPR research projects are funded separately, while the CEED Hub provides centralized services and leadership that benefit all projects. In addition to support from the CEED Hub, the CBPR projects will receive consultative services from the NIH Community Engagement Alliance Consultative Resource (CEACR). They will also participate in the Science Collaborative for Health and Artificial Intelligence Reduction of Errors (SCHARE) platform, indicating that the consortium intends to strengthen data practices and potentially leverage modern analytic approaches while paying attention to error reduction and responsible use. The overarching goal across these connected pieces is to promote meaningful, transformational community engagement alongside stronger data use, with the practical aim of optimizing oral health for all communities.
The CEED Hub is expected to coordinate communications and core consortium functions across three main domains. First, it will provide data planning, consultation, and technical assistance focused on research methodology and analytics. In practical terms, this implies the hub will help projects think through common data elements, data quality, harmonization, analytic plans, and potentially shared tools or workflows that allow findings to be compared or aggregated across sites. The second domain is community engagement evaluation, which points to a formal effort to assess how community-engaged approaches are implemented across the consortium, how well they function, and what outcomes they produce for partnership quality, trust, shared decision-making, and the ability to translate evidence into practice. The third domain is ADAPT infrastructure and operational support, meaning the hub will handle the operational backbone of the consortium such as coordination logistics, meeting support, cross-project communication structures, documentation, and other shared processes required for a multi-site, multi-partner research program to run smoothly.
The award is offered as a discretionary federal assistance opportunity using the cooperative agreement model, which generally means NIH will have substantial programmatic involvement compared with a standard research grant. While the specific details of that involvement are described in the full NOFO, applicants should expect an ongoing relationship with NIH staff and expectations around coordination, deliverables, and consortium-wide participation rather than operating in isolation. The opportunity is listed under health-related funding activity and references CFDA numbers 93.121, 93.310, and 93.313, reflecting its placement within NIH assistance programs.
Eligibility is broad across many U.S.-based organization types, including various levels of government (state, county, city/township, special districts), independent school districts, public housing authorities/Indian housing authorities, institutions of higher education (public and private), tribal governments and tribal organizations, nonprofits with or without 501(c)(3) status (excluding higher education institutions in those nonprofit categories), for-profit organizations (including those other than small businesses), small businesses, and other eligible entities as defined in the NOFO. A key limitation is that foreign organizations are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components are not allowed as defined by NIH policy. In short, the hub must be fully domestic in both applicant status and project components.
Administratively, the funding opportunity is titled "Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)," with Funding Opportunity Number RFA-DE-27-001, issued by the National Institutes of Health. The original application closing date is listed as 2026-10-19. The expected number of awards is 1, reinforcing that NIH is looking for a single, centralized hub to serve the entire ADAPT consortium rather than multiple regional hubs. An award ceiling is not specified in the provided summary, so applicants would need to consult the full NOFO for budget guidance and any caps or recommended budget ranges.
Taken together, this opportunity is best understood as a backbone and enabling-center grant: the CEED Hub is meant to strengthen the quality, consistency, and impact of multiple community-based oral health projects by providing shared data coordination and analytic support, rigorously evaluating community engagement processes, and running the operational infrastructure that keeps the consortium aligned. The emphasis on CBPR, formal engagement evaluation, and participation in broader NIH-supported consultative and data platforms signals an intent to build not only research results, but also durable, scalable practices for how community-engaged oral health research is designed, measured, and translated into real-world improvements.Apply for RFA DE 27 001
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.310, 93.313.
- This funding opportunity was created on 2026-04-27.
- Applicants must submit their applications by 2026-10-19. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
1) What is this NIH funding opportunity?
This opportunity funds a single Community Engagement Evaluation and Data Coordination (CEED) Hub under a cooperative agreement (U01) to support a larger Community-Based Participatory Research (CBPR) consortium called Advancing Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All.
2) What is the official title and funding opportunity number?
The title is "Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)." The Funding Opportunity Number is RFA-DE-27-001.
3) Who is the sponsoring agency?
The sponsoring agency is the National Institutes of Health (NIH).
4) What is ADAPT, and how does the CEED Hub fit into it?
ADAPT is a CBPR consortium focused on improving oral health outcomes and reducing inequities. Individual CBPR research projects are funded separately, and the CEED Hub serves as the coordinating center that provides shared leadership, infrastructure, and cross-project support so the consortium can operate in a consistent, collaborative, and data-driven way.
5) How many awards will NIH make?
NIH expects to make 1 award, meaning one CEED Hub will serve the entire ADAPT consortium.
6) What is the application due date listed in the summary?
The original application closing date listed is 2026-10-19.
7) Is this opportunity intended to fund clinical trials?
No. The opportunity is explicitly marked "Clinical Trial Not Allowed." The CEED Hub is intended to provide coordination, evaluation, and analytic infrastructure rather than run clinical trials.
8) What are the main responsibilities of the CEED Hub?
The CEED Hub is expected to coordinate communications and core consortium functions across three domains:
- Data planning, consultation, and technical assistance focused on research methodology and analytics (for example, common data elements, data quality, harmonization, and analytic planning).
- Community engagement evaluation to assess how community-engaged approaches are implemented and what outcomes they produce (such as partnership quality, trust, shared decision-making, and translation to practice).
- ADAPT infrastructure and operational support (coordination logistics, meeting support, cross-project communications, documentation, and shared processes).
9) What does "data coordination" mean in this context?
Based on the summary, data coordination includes supporting projects with shared data practices such as developing or aligning common data elements, improving data quality, harmonizing data across sites, helping with analytic plans, and potentially enabling shared tools or workflows so results can be compared or aggregated across projects.
10) What does "community engagement evaluation" mean for the CEED Hub?
Community engagement evaluation refers to a formal, consortium-wide effort to assess how community-engaged approaches are carried out and how well they function. The summary highlights evaluation outcomes such as partnership quality, trust, shared decision-making, and the ability to translate evidence into practice.
11) What operational or infrastructure support is the Hub expected to provide?
The CEED Hub is expected to provide the operational backbone of the consortium, including coordination logistics, meeting support, cross-project communication structures, documentation, and other shared processes needed for a multi-site, multi-partner research program.
12) How are the CBPR research projects funded relative to the CEED Hub?
The CBPR research projects are funded separately. The CEED Hub is funded to provide centralized services and leadership that benefit all those separately funded projects.
13) What other NIH-supported resources will CBPR projects receive in addition to support from the CEED Hub?
The summary states that the CBPR projects will receive consultative services from the NIH Community Engagement Alliance Consultative Resource (CEACR) and will participate in the Science Collaborative for Health and Artificial Intelligence Reduction of Errors (SCHARE) platform.
14) What is the CEACR in this program structure?
Within the ADAPT structure described, CEACR is an NIH consultative resource that provides consultative services to the CBPR projects alongside the coordination provided by the CEED Hub.
15) What is SCHARE, and why is it mentioned?
SCHARE is referenced as a platform in which the consortium will participate. The summary suggests this signals an intent to strengthen data practices and potentially leverage modern analytic approaches while emphasizing error reduction and responsible use.
16) What is the funding mechanism, and what does it imply?
The mechanism is a cooperative agreement (U01). In general, a cooperative agreement implies substantial programmatic involvement from NIH compared with a standard research grant, including ongoing collaboration, coordination expectations, deliverables, and consortium-wide participation rather than operating independently.
17) What types of organizations are eligible to apply?
Eligibility is described as broad for U.S.-based entities, including:
- State, county, city/township governments, and special district governments
- Independent school districts
- Public housing authorities/Indian housing authorities
- Institutions of higher education (public and private)
- Tribal governments and tribal organizations
- Nonprofits with or without 501(c)(3) status (in the nonprofit categories described, excluding higher education institutions)
- For-profit organizations (including those other than small businesses)
- Small businesses
- Other eligible entities as defined in the NOFO
18) Are foreign organizations eligible to apply?
No. Foreign organizations are not eligible to apply.
19) Can a U.S. organization include non-U.S. components or foreign components?
No. The summary states that non-U.S. components of U.S. organizations are not eligible, and foreign components are not allowed as defined by NIH policy. The CEED Hub must be fully domestic in both applicant status and project components.
20) What is the primary goal of the CEED Hub and the ADAPT consortium?
The overall goal is to improve oral health outcomes and reduce inequities by promoting meaningful, transformational community engagement and stronger, more consistent data use across multiple community-based projects, with an emphasis on durable and scalable practices for community-engaged oral health research and translation into real-world improvements.
21) What is the CFDA assistance listing information referenced?
The summary references CFDA numbers 93.121, 93.310, and 93.313 as the assistance listings associated with this NIH health-related funding activity.
22) Is there an award ceiling stated in the provided summary?
No. The provided summary does not specify an award ceiling. It notes that applicants would need to consult the full NOFO for budget guidance and any caps or recommended budget ranges.
23) What does it mean that this is a "backbone" or enabling-center grant?
Based on the summary, the CEED Hub is meant to enable and strengthen the work of multiple separately funded CBPR projects by providing shared coordination, evaluation, analytics support, and operational infrastructure that keeps the consortium aligned and functioning effectively.
24) What kind of consortium-wide benefits is the CEED Hub expected to deliver?
The summary emphasizes consortium-wide benefits including consistent and collaborative data practices, improved ability to compare or aggregate findings across sites, rigorous evaluation of community engagement processes, and efficient operations that support multi-site communication and shared decision-making.
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